Mouse lung infected with "fluorescent influenza viruses"

Endangered crane species on the Izumi plain

Rope-based oral fluid sampling from piglets

PED virus-induced syncytium formation

Collection of oral fluid from Japanese pipistrelle bats

AI camera-based chicken activity analysis

Domain of research

  • Virus
  • Livestock
  • Wildlife

At our laboratory, we focus on knowledge and techniques in the field of virology. Our extensive research is dominated by the terms "Virus", "Livestock", and "Wildlife". We conduct our research mainly in Kagoshima, south-western Japan, a region rich in nature which is also one of the country's foremost livestock-producing areas, actively collaborating with both public bodies and private enterprises. We pioneer research activities and disseminate information, concentrating on the diverse contributions we can make to society.

Mouse lung infected with "fluorescent influenza viruses"

Enhancing and applying "reverse genetics" system for influenza virus

Many viruses can now be artificially generated with fully retained infectivity, replication ability, and pathogenicity, due to a remarkable breakthrough in genetic engineering technology: reverse genetics system. The influenza virus was one of the earliest to be subject to this technology, which means that artificial influenza viruses have become more than just an effective and useful research tool; researchers are now actively trying to utilize them for clinical applications. At our laboratory, we are striving both to enhance this technology and to develop its real-world applications.

Endangered crane species on the Izumi plain

Avian influenza surveillance in a wild population

High pathogenicity avian influenza viruses are now a major threat to the poultry industry, and circulate among ducks and other wild waterfowl. These viruses are spread as birds seasonally migrate over great distances. For our research in this field, we have targeted the Izumi Plain, which is a major overwintering ground of wild waterfowl including endangered cranes. We collect environmental samples and wild bird carcasses for virological examinations, and subject them to genetic analysis to determine the prevalence and strains of circulating avian influenza viruses.

Rope-based oral fluid sampling from piglets

Characterization of swine influenza viruses circulating in Japan

Swine influenza viruses are of course a health hazard for pigs, but they also cause concern over their potential zoonotic transmission to people. These pathogens thus represent a crucial challenge for both livestock and public health, and characterizing the viruses and establishing systems to control them meet major social needs. At our laboratory, we exploit our reverse genetics techniques for influenza viruses, to characterize and study each swine influenza virus strain circulating in Japan.

PED virus-induced syncytium formation

Infectious livestock disease virology

Infectious livestock diseases have a major negative impact. They are not just a health hazard for animals and a cause of economic loss for farmers; the concomitant shortfalls in food supply and rises in food prices create confusion and anxiety for consumers. When the disease is a virus, prevention is key, because viruses cannot be treated with antibiotics as bacteria can. The preventive measures include vaccinations, maintaining regional virus-free status, and halting virus spread. At our laboratory, we exploit molecular biological techniques and knowledge developed in the field of influenza research, to investigate a range of viruses which can infect livestock.

Collection of oral fluid from Japanese pipistrelle bats

Infectious wildlife disease virology

Infectious wildlife diseases pose a potential threat to all people, livestock, and wild animals in an outbreak area, as well as any directly affected animals, and thus represent an area of research that should be taken seriously. However, wildlife diseases are much less well investigated than human or domesticated animal diseases, because of the many obstacles to research in wild animals. In our laboratory, we elucidate the dynamics of virus infections and detect new viruses, collaborating with relevant governmental agencies.

Endangered crane species on the Izumi plain

Pioneering and propagating "smart animal husbandry"

The Japanese livestock industry is embracing smart technologies to solve issues ranging from manpower shortages to decreased productivity. Solutions are provided by cutting-edge information and communication technology (ICT), artificial intelligence (AI), and robot technology, and much more can be expected from these smart technologies. As our contribution in this area, we are developing “smart animal husbandry” focusing on pigs and broiler chickens, in collaboration with enterprises and producers. We are taking the technologies we pioneer to the point of production and propagation.

Faculty Members

Makoto Ozawa, DVM, PhD

title
Associate Professor
Virology, Animal Health

Kosuke Okuya, DVM, PhD

title
Assistant Professor
Virology

Students

Mana Esaki, DVM

title
2nd-year PhD Student

Qianxi Zhou

title
Research Student
(2nd-year MC Student, Hunan Agricultural University)

Inori Goda

title
6th-year Undergraduate Student

Sho Sata

title
6th-year Undergraduate Student

Shiori Osuga

title
5th-year Undergraduate Student

Saiko Sawai

title
5th-year Undergraduate Student

Support Staffs

Natsuko Nishi

title
Research Assistant

Donna Koyamada

title
Administrative Assistant

Rara Saito

title
Research Assistant

Maki Inaba

title
Techinical Assistant

Shizuka Hirose, DVM

title
External Research Collaborator

Keiko Yoshitomi

title
Research Assistant

Access

Department of Pathogenetic and Preventive Veterinary Science,
Joint Faculty of Veterinary Medicine,
Kagoshima University
1-21-24 Korimoto, Kagoshima 890-0065, Japan
Campus Map
Contact
Tel: +81-99-285-3651
E-mail: mozawa@vet.kagoshima-u.ac.jp
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